Dr. Paul Schimmel is Professor of Molecular Medicine and of Chemistry at Scripps Research Institute. He also holds an appointment with the Institute for Advanced Study at Hong Kong University of Science and Technology, is the author of a widely used three volume textbook on biophysical chemistry, and is a co-founder or founding director of eleven biotechnology companies that develop new therapies for human diseases and disorders. Though Paul began his studies intent on becoming a medical doctor, he became fascinated by the fields of biophysics and biophysical chemistry along the way. His research answers fundamental questions about the origin of life and the genetic code. In his work with a variety of biotech companies, Paul is also translating his laboratory research to create new medicines that leverage key processes, mechanisms, and molecules employed naturally by our bodies. When he’s not hard at work, Paul loves getting out on the water on his powerboat. For over two decades, he and his wife have enjoyed exploring the islands and coasts of the Pacific Northwest. Paul earned his B.A. in Pre-Medicine from Ohio Wesleyan University and his Ph.D. in biochemistry and biophysics at MIT. He did a short postdoc at Stanford before joining the faculty at MIT. Paul served on the faculty at MIT for 30 years, and prior to coming to Scripps, he was the John D. and Catherine T. MacArthur Professor of Biochemistry and Biophysics in the Department of Biology there. Throughout his career, he has received numerous awards and honors, including being named an elected Member of the American Academy of Arts and Sciences, the National Academy of Sciences, the American Philosophical Society, the Institute of Medicine of the National Academy of Medicine, and the National Academy of Inventors. In addition, Paul received the American Chemical Society's 2020 Kathryn C. Hach Award for Entrepreneurial Success, the 2020 Scientist of the Year Award from the San Diego Chapter of the Achievement Rewards for College Scientists (ARCS) Foundation, the Harvard University Frank Westheimer Medal, the American Chemical Society's Pfizer Award in Enzyme Chemistry, the Biophysical Society’s Emily M. Gray Award for Significant Contributions to Education in Biophysics, the Chinese Biopharmaceutical Association Brilliant Achievement Award, the Stein and Moore Award of the Protein Society, and an Honorary Doctor of Science Degree from Ohio Wesleyan University and the Kellogg School of Science and Technology at Scripps Research. In our interview, Paul shares insights from his life and science.

Direct download: 607_Paul_Schimmel_Final.mp3
Category:general -- posted at: 3:00am EDT

Dr. Wakenda Tyler is an Associate Professor in Orthopaedic Oncology and Metabolic Bone Disease and Adult Reconstruction at the University of Rochester Medical Center. Wakenda is an orthopedic surgical oncologist. She is an orthopedic surgeon with a clinical and research focus on cancerous tumours found in bones, tendon, soft tissue, ligament, and muscles. Wakenda spends her time outside of the science and medicine doing a wide variety of activities. For her, running is a great way to relax and she enjoys running in races, especially charity events. She also likes to go snowboarding, skiing, hiking, scuba diving, and traveling to new places. She was awarded her M.D. And M.P.H. from John Hopkins University and completed residency in Orthopaedic Surgery at the Hospital for Special Surgery. Wakenda then completed a fellowship in musculoskeletal oncology at the Memorial Sloan Kettering Cancer Center before joining the faculty at the University of Rochester where she is today. Wakenda is with us today to tell us all about her journey through life and science.

Direct download: 606_Wakenda_Tyler_Final_V2.mp3
Category:general -- posted at: 3:00am EDT

Dr. Shailesh Kantak is a clinician scientist, an Institute Scientist, and Director of the Neuroplasticity and Motor Behavior Laboratory at Moss Rehabilitation Research Institute (MRRI). He is also a recently tenured Assistant Professor in the Department of Physical Therapy at Arcadia University. Shailesh is dedicated to helping people with neurological injuries recover better and more quickly. He is interested in understanding why some people respond well to treatments and recover more fully, while others do not. Cooking and sharing homemade meals with friends are two things that bring Shailesh a lot of joy. He also enjoys gardening and traveling (though he hasn’t been able to travel much lately). Shailesh received his Bachelor of Science degree in Physical Therapy from Seth G.S. Medical College and KEM Hospital at Mumbai University. He went on to earn his Master of Science degree in Physical Therapy with a specialization in Neurologic Physical Therapy from Mumbai University as well. Afterwards, Shailesh attended the University of Southern California where he was awarded his PhD in Biokinesiology. Next, he conducted postdoctoral research at the Rehabilitation Institute of Chicago and subsequently the University of Maryland, Baltimore. In our interview, Shailesh shares more about his life and research.

Direct download: 605_Shailesh_Kantak_Final.mp3
Category:general -- posted at: 3:00am EDT

Professor Dame Kay Davies is the Dr. Lee's Professor of Anatomy in the Department of Physiology, Anatomy and Genetics and Director of the MRC Functional Genomics Unit at the University of Oxford. She is also the Honorary Director of the MRC Functional Genomics Unit, a deputy chairman of the Wellcome Trust, and Executive Editor of the journal Human Molecular Genetics. Kay is also a co-founder of a biotechnology company and is a director of another. In her research, Kay uses genetics techniques to help find effective treatments for muscular dystrophy. Much of her work has focused on Duchenne Muscular Dystrophy, a severe and progressive muscle wasting disease that primarily affects males. When she’s not working, Kay loves taking walks in the English countryside, listening to classical music, and playing the piano. She completed her undergraduate studies at Somerville College and served as a Junior Research Fellow at Wolfson College in Oxford. She then completed a postdoctoral fellowship at the Saclay Nuclear Research Center, and went on to serve as a research fellow at St. Mary's Hospital Medical School and John Radcliffe Hospital and then as a faculty member at John Radcliffe Hospital and the University of London before joining the faculty at Oxford. Kay has received many awards and honors during her career, and to name just a few, she was elected as a founding Fellow of the Academy of Medical Sciences and a Fellow of the Royal Society. She was also named Commander of the Order of the British Empire and then Dame Commander of the Order of the British Empire. Kay is also an Honorary Fellow of Sommerville College, and had the honor of giving the inaugural Rose lecture at Kingston University in 2012 and the Harveian Oration at the Royal College of Physicians in 2013. In our interview, Kay tells us more about her journey through life and science.

Direct download: 604_Kay_Davies_Rebroadcast_Final.mp3
Category:general -- posted at: 3:00am EDT

Dr. Charles Cockell is a Professor of Astrobiology in the School of Physics and Astronomy at the University of Edinburgh and Director of the UK Centre for Astrobiology. In addition, he is the Founder and Chair of the Earth and Space Foundation and also the Co-Founder, current Board Member, and Past President of the Association of Mars Explorers. Charles has also been elected as an International Fellow of the Explorers Club. His work examines how life has emerged and has persisted on our planet and beyond. One of Charles's favorite things to do when he's not at work is go walking out in the hills and wilderness. It's a great way to clear his mind and enjoy the outdoors. He did his undergraduate training in Biochemistry and Molecular Biology at Bristol University and received his PhD in Molecular Biophysics from the University of Oxford. Prior to joining the faculty at the University of Edinburgh, Charles was a National Academy of Sciences Associate with NASA, a visiting Scholar at both Stanford University and the University of Arizona, a Research Scientist with the British Antarctic Survey, and also Professor of Geomicrobiology at Open University. In this episode, Charles discusses, his life, science, and more.

Direct download: 603_Charles_Cockell_Rebroadcast_Final.mp3
Category:general -- posted at: 3:00am EDT

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